Yes. Much, much smaller. A 5 minute tut in Wink is around 2mb to 3mb. A 5 minute tut after compression with openshot video editor is around 90mb to 100mb.
Unfortunately Wink tutorials can not be submitted to YouTube as is, so I was ending up recapturing the tut with Xvidcap, putting me right back to a bigger file size.
Uploading to YouTube and letting their compression software do its thing will take one of openshots video's and shrink it again. For example the ssh tut was 160mb when I uploaded it, when I download it from YouTube after it runs through their compression software it is only 40.9mb.