Vector Linux was what I started on years ago, but somewhat recently I tried Debian and was happy to see some of the Humble Indie Bundle games ran correctly under it that wouldn't work under VL. I've stuck with it for about half a year, getting into a few fist fights with the package manager not liking me manually updating one package to unstable (everything worked fine, but it insisted there were broken dependencies that HAD to be fixed before it could modify anything else on my system. Result: started using dpkg manually instead of apt-get). I also ran into problems trying to compile things from source (which I've been doing as long as I've used Linux), because the packages needed to build things were scattered about. I have come to the conclusion that I am simply a Slackware kind of guy. Vector Linux is nice because it's made to be comfortable to use, but it takes the Slackware point of view where it gives you all the tools to hack things yourself. As of a few days ago, I've got VL7 up and running on my main computer, and it's doing pretty well.
I've got a light-duty web server running Slackware...13? It seems like the simplest, most no-nonsense way to run a server, just using the first disk. The list of running processes doesn't even fill my screen in htop. Beautiful.