I guess the answer is yes:
Well, I'll be darned!
Armed with all the information you folks so generously provided, I installed the Vector Gold VL5.8 to my second boot disk, went and got the NVidia driver I needed, installed it, got Twinview enabled and working
, mounted a disk with my .mozilla directoriy and copied it over, and I'm up and running in Vector Linux!
I think there is nothing special in vl related to Twinview, the process should be like in any other linux distro.